Uremia is a disease of catabolism (breaking down of tissues)
with
evidence of (tissue) weight loss and malnutrition. Dialysis
and
transplant reverse this when they work well. For HD the URR
should be
above 65% (Kt/v >1.4) and with further study may turn out
to be higher.
Those who are well dialyzed should have the appetite to eat
well enough
to return toward their pre-illness real weight. Poor
appetite and real
weight loss must always be signs of great concern to the
nephrologist
since, if not due to underdialysis, they indicate another
severe illness
is lurking and should be searched for.
Peter Lundin
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